Both maitake and shiitake mushrooms have been traditionally used in medicine to support immune function, cardiovascular health, and overall wellbeing. Maitake has been found to contain compounds that may help inhibit tumor growth and lower blood sugar levels. It is also rich in vitamins and minerals such as B vitamins, vitamin D, selenium, copper, and zinc. Shiitake contains polysaccharides that are believed to have immune-boosting properties, as well as eritadenine, which may help lower cholesterol levels. Additionally, it is rich in antioxidants and anti-inflammatory compounds that may help reduce inflammation throughout the body. Both mushrooms are considered safe when consumed in reasonable amounts as part of a healthy diet, but those with allergies or sensitivities to mushrooms should avoid them.